Louisville Cardinals vs Pittsburgh Panthers odds · Nov 21, 3:30 PM ET
Next meeting: Pittsburgh Panthers @ Louisville Cardinals, Nov 21, 3:30 PM ET. Best moneyline: Pittsburgh Panthers +375 at FanDuel, Louisville Cardinals -322 at Kalshi (after fees). Best spread price: Pittsburgh Panthers +12.5 -110 at FanDuel. Every sportsbook, Kalshi and Polymarket price (after fees) is below, as of Nov 15, 3:48 AM ET. The page re-prices every 5 minutes until the game starts, so an older copy of it is out of date; this address always has the current prices. Bold marks the best payout. Prices move — always confirm at the book.
Sportsbooks make Louisville Cardinals a 80% favorite over Pittsburgh Panthers (20%) for Nov 21: each book’s moneyline with its margin removed, averaged across 1 book. That describes the market, not a prediction.
Pittsburgh Panthers @ Louisville Cardinals odds · Nov 21, 3:30 PM ET
Best price on the Pittsburgh Panthers is +375 at FanDuel; best on the Louisville Cardinals is -322 at Kalshi (after fees).
Moneyline
| Book | Pittsburgh Panthers ML | Louisville Cardinals ML |
|---|---|---|
| FanDuel | +375 · best | -490 |
| Kalshi (after fees) | +280 | -322 · best |
Spread
Best spread price: Pittsburgh Panthers +12.5 is -110 at FanDuel, Louisville Cardinals -12.5 is -110 at FanDuel.
| Book | Pittsburgh Panthers +12.5 | Louisville Cardinals -12.5 |
|---|---|---|
| FanDuel | -110 · best | -110 · best |
Total 52.5
Best total price: Over 52.5 is -110 at FanDuel, Under 52.5 is -110 at FanDuel.
| Book | Over 52.5 | Under 52.5 |
|---|---|---|
| FanDuel | -110 · best | -110 · best |
Pittsburgh Panthers vs Louisville Cardinals prediction: what the market says
Who will win Pittsburgh Panthers vs Louisville Cardinals?
Nobody knows, but the market leans Louisville Cardinals. Sportsbooks give Louisville Cardinals a 80% chance to win and Pittsburgh Panthers 20%: 1 book’ moneylines with the margin taken out, averaged. Prediction-market traders pay 75¢ on Kalshi for a Louisville Cardinals win: cents on the dollar, so about that chance in percent, before fees. That is what the prices say, not a pick: Oddy makes none.
What is the predicted score for Pittsburgh Panthers vs Louisville Cardinals?
This page makes no prediction; the betting lines imply one. The spread (Louisville Cardinals -12.5) and the total (52.5) add up to a score near Louisville Cardinals 32.5, Pittsburgh Panthers 20. Lines move until the game starts.
Louisville Cardinals vs Pittsburgh Panthers best odds by state
The best price on each side among the sportsbooks and prediction markets that take bets in each state, as of Nov 15, 3:48 AM ET. A state not listed has nothing priced on both sides of this game. Which books take bets where was last checked Nov 13, 2026.
Best price in 49 states
| State | Pittsburgh Panthers moneyline | Louisville Cardinals moneyline | Pittsburgh Panthers spread | Louisville Cardinals spread |
|---|---|---|---|---|
| Alabama | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Alaska | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Arizona | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Arkansas | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| California | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Colorado | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Connecticut | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Delaware | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Florida | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Georgia | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Hawaii | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Idaho | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Illinois | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Indiana | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Iowa | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Kansas | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Kentucky | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Louisiana | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Maine | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Maryland | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Massachusetts | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Michigan | +375 at FanDuel | -490 at FanDuel | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Minnesota | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Mississippi | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Missouri | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Montana | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Nebraska | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| New Hampshire | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| New Jersey | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| New Mexico | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| New York | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| North Carolina | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| North Dakota | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Ohio | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Oklahoma | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Oregon | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Pennsylvania | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Rhode Island | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| South Carolina | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| South Dakota | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Tennessee | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Texas | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Utah | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Vermont | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Virginia | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Washington, D.C. | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| West Virginia | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
| Wisconsin | +280 at Kalshi (after fees) | -322 at Kalshi (after fees) | — | — |
| Wyoming | +375 at FanDuel | -322 at Kalshi (after fees) | +12.5 -110 at FanDuel | -12.5 -110 at FanDuel |
Louisville Cardinals vs Pittsburgh Panthers odds questions
When do Louisville Cardinals and Pittsburgh Panthers play next?
Pittsburgh Panthers @ Louisville Cardinals is Saturday, November 21 at 3:30 PM ET. Every sportsbook, Kalshi and Polymarket price on it is on this page until it starts.
Who is favored in Louisville Cardinals vs Pittsburgh Panthers?
Sportsbooks make Louisville Cardinals a 80% favorite over Pittsburgh Panthers (20%) for Nov 21: each book’s moneyline with its margin removed, averaged across 1 book. That describes the market, not a prediction.
What are the best odds for Louisville Cardinals vs Pittsburgh Panthers?
Best moneyline: Pittsburgh Panthers +375 at FanDuel, Louisville Cardinals -322 at Kalshi (after fees). Best spread price: Pittsburgh Panthers +12.5 -110 at FanDuel.
What is Oddy?
Oddy shows what every regulated sportsbook and prediction market pays for the same bet, ranked, with a link to the best price. Prices refresh every 5 minutes before a game; once it starts, Kalshi and Polymarket are re-read every 5 seconds from their own APIs (how Oddy works). Free, no account, and we never sell picks.