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Pittsburgh Panthers vs Louisville Cardinals odds · Nov 21, 3:30 PM ET

Pittsburgh Panthers @ Louisville Cardinals: moneyline, spread and total at 2 books, as of Nov 15, 3:38 AM ET. The page re-prices every 5 minutes until the game starts, so an older copy of it is out of date; this address always has the current prices. Bold marks the best payout. Prices move — always confirm at the book.

Sportsbooks make the Louisville Cardinals a 79% favorite over the Pittsburgh Panthers (21%): each book’s moneyline with its margin removed, averaged across 1 book. That describes the market, not a prediction.

Every book’s price, game by game (as of Nov 15, 3:38 AM ET)

Pittsburgh Panthers @ Louisville Cardinals odds · Nov 21, 3:30 PM ET

Best price on the Pittsburgh Panthers is +360 at FanDuel; best on the Louisville Cardinals is -322 at Kalshi (after fees).

Moneyline

BookPittsburgh Panthers MLLouisville Cardinals ML
FanDuel+360 · best-465
Kalshi (after fees)+252-322 · best

Spread

Best spread price: Pittsburgh Panthers +11.5 is -110 at FanDuel, Louisville Cardinals -11.5 is -110 at FanDuel.

BookPittsburgh Panthers +11.5Louisville Cardinals -11.5
FanDuel-110 · best-110 · best

Total 52.5

Best total price: Over 52.5 is -110 at FanDuel, Under 52.5 is -110 at FanDuel.

BookOver 52.5Under 52.5
FanDuel-110 · best-110 · best

Pittsburgh Panthers vs Louisville Cardinals odds questions

Who is favored in Pittsburgh Panthers vs Louisville Cardinals?

Sportsbooks make the Louisville Cardinals a 79% favorite over the Pittsburgh Panthers (21%): each book’s moneyline with its margin removed, averaged across 1 book. That describes the market, not a prediction.

What are the best odds for Pittsburgh Panthers vs Louisville Cardinals?

Best moneyline: Pittsburgh Panthers +360 at FanDuel, Louisville Cardinals -322 at Kalshi (after fees). Best spread: Pittsburgh Panthers +11.5 -110 at FanDuel, Louisville Cardinals -11.5 -110 at FanDuel. Best total: over 52.5 -110 at FanDuel, under -110 at FanDuel.

When does Pittsburgh Panthers vs Louisville Cardinals start?

Pittsburgh Panthers vs Louisville Cardinals starts Saturday, November 21 at 3:30 PM ET. This page shows pre-game prices; they come off the board once it starts.

Pittsburgh Panthers vs Louisville Cardinals prediction: what the market says

Who will win Pittsburgh Panthers vs Louisville Cardinals?

Nobody knows, but the market leans Louisville Cardinals. Sportsbooks give Louisville Cardinals a 79% chance to win and Pittsburgh Panthers 21%: 1 book’ moneylines with the margin taken out, averaged. Prediction-market traders pay 75¢ on Kalshi for a Louisville Cardinals win: cents on the dollar, so about that chance in percent, before fees. That is what the prices say, not a pick: Oddy makes none.

What is the predicted score for Pittsburgh Panthers vs Louisville Cardinals?

This page makes no prediction; the betting lines imply one. The spread (Louisville Cardinals -11.5) and the total (52.5) add up to a score near Louisville Cardinals 32, Pittsburgh Panthers 20.5. Lines move until the game starts.

Pittsburgh Panthers vs Louisville Cardinals best odds by state

The best price on each side among the sportsbooks and prediction markets that take bets in each state, as of Nov 15, 3:38 AM ET. A state not listed has nothing priced on both sides of this game. Which books take bets where was last checked Nov 13, 2026.

Best price in 49 states
StatePittsburgh Panthers moneylineLouisville Cardinals moneylinePittsburgh Panthers spreadLouisville Cardinals spread
Alabama+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Alaska+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Arizona+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Arkansas+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
California+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Colorado+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Connecticut+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Delaware+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Florida+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Georgia+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Hawaii+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Idaho+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Illinois+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Indiana+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Iowa+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Kansas+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Kentucky+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Louisiana+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Maine+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Maryland+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Massachusetts+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Michigan+360 at FanDuel-465 at FanDuel+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Minnesota+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Mississippi+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Missouri+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Montana+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Nebraska+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
New Hampshire+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
New Jersey+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
New Mexico+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
New York+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
North Carolina+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
North Dakota+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Ohio+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Oklahoma+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Oregon+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Pennsylvania+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Rhode Island+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
South Carolina+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
South Dakota+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Tennessee+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Texas+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Utah+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Vermont+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Virginia+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Washington, D.C.+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
West Virginia+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel
Wisconsin+252 at Kalshi (after fees)-322 at Kalshi (after fees)——
Wyoming+360 at FanDuel-322 at Kalshi (after fees)+11.5 -110 at FanDuel-11.5 -110 at FanDuel

Pittsburgh Panthers vs Louisville Cardinals: next game, past results and closing odds

All NCAAF odds

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What is Oddy?

Oddy shows what every regulated sportsbook and prediction market pays for the same bet, ranked, with a link to the best price. Prices refresh every 5 minutes before a game; once it starts, Kalshi and Polymarket are re-read every 5 seconds from their own APIs (how Oddy works). Free, no account, and we never sell picks.