Lions vs Bills odds · Sep 17, 8:15 PM ET
Detroit Lions @ Buffalo Bills: moneyline, spread and total at 9 books, as of Sep 10, 9:11 PM ET. Bold marks the best payout. Prices move — always confirm at the book.
Detroit Lions @ Buffalo Bills odds · Sep 17, 8:15 PM ET
Best price on the Lions is +164 at FanDuel; best on the Bills is -162 at DraftKings. Best and worst sportsbook are $28 apart on a $100 bet.
Moneyline
| Book | Detroit Lions ML | Buffalo Bills ML |
|---|---|---|
| FanDuel | +164 · best | -196 |
| Kalshi (after fees) | +152 | -182 |
| theScore Bet | +145 | -170 |
| Polymarket (after fees) | +143 | -179 |
| Caesars | +141 | -170 |
| Bally Bet | +140 | -175 |
| betPARX | +140 | -175 |
| BetRivers | +140 | -175 |
| DraftKings | +136 | -162 · best |
Spread
Best spread price: Detroit Lions +3 is -103 at Caesars, Buffalo Bills -3 is -112 at Bally Bet. Best and worst sportsbook are $5 apart on a $100 bet.
| Book | Detroit Lions +3 | Buffalo Bills -3 |
|---|---|---|
| Caesars | -103 · best | -117 |
| DraftKings | -105 | -115 |
| Bally Bet | -109 | -112 · best |
| betPARX | -109 | -112 · best |
| BetRivers | -109 | -112 · best |
Total 52.5
Best total price: Over 52.5 is -105 at theScore Bet, Under 52.5 is -110 at FanDuel. Best and worst sportsbook are $4 apart on a $100 bet.
| Book | Over 52.5 | Under 52.5 |
|---|---|---|
| theScore Bet | -105 · best | -115 |
| Bally Bet | -109 | -112 |
| betPARX | -109 | -112 |
| BetRivers | -109 | -112 |
| FanDuel | -110 | -110 · best |
| Kalshi (after fees) | -116 | -116 |
More NFL games
Falcons vs Steelers · Sep 13, 1:00 PM ET · Ravens vs Colts · Sep 13, 1:00 PM ET · Bills vs Texans · Sep 13, 1:00 PM ET · Bears vs Panthers · Sep 13, 1:00 PM ET · Buccaneers vs Bengals · Sep 13, 1:00 PM ET · Browns vs Jaguars · Sep 13, 1:00 PM ET · Saints vs Lions · Sep 13, 1:00 PM ET · Jets vs Titans · Sep 13, 1:00 PM ET · Cardinals vs Chargers · Sep 13, 4:25 PM ET · Packers vs Vikings · Sep 13, 4:25 PM ET · Dolphins vs Raiders · Sep 13, 4:25 PM ET · Commanders vs Eagles · Sep 13, 4:25 PM ET · Cowboys vs Giants · Sep 13, 8:20 PM ET · Broncos vs Chiefs · Sep 14, 8:15 PM ET
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